Strawberry notch homolog 2 regulates the response to interleukin-6 in the central nervous system.

Taylor E SymeMagdalena GrillEmina HayashidaBarney ViengkhouIain L CampbellMarkus J Hofer

Published in: Journal of neuroinflammation (2022)

Based on these results, we propose a role for SBNO2 as a novel negative feedback regulator of IL-6 that restrains the excessive inflammatory actions of this cytokine in the brain.

Keyphrases

resting state
oxidative stress
cell proliferation
weight gain
transcription factor
cerebrospinal fluid
functional connectivity
cerebral ischemia
multiple sclerosis
body mass index
subarachnoid hemorrhage
blood brain barrier