Integrative Analysis of the Roles of lncRNAs and mRNAs in Itaconate-Mediated Protection Against Liver Ischemia-Reperfusion Injury in Mice.
Yanan XuZihao LiShounan LuChaoqun WangShanjia KeXinglong LiBing YinHongjun YuMenghua ZhouShangha PanHongchi JiangYong MaPublished in: Journal of inflammation research (2021)
Our study revealed that itaconate could protect the liver against IR injury and that lncRNAs might play a role in this process. Our study provides a novel way to investigate the mechanism by which itaconate affects hepatic IR injury and exerts its anti-inflammatory and antioxidative stress effects.