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Corticopallidal Connectome of the Globus Pallidus Externus in Humans: An Exploratory Study of Structural Connectivity Using Probabilistic Diffusion Tractography.

Sanjeet S GrewalVanessa Milanese Holanda ZimpelErik H Middlebrooks
Published in: AJNR. American journal of neuroradiology (2018)
Our in vivo study of the human globus pallidus externus using probabilistic tractography supports the existence of extensive corticopallidal connections and a tripartite functional division, as found in animal studies. A better understanding of the connectivity of the globus pallidus externus may help to understand its function and elucidate the effects of programming the higher contacts in pallidal deep brain stimulation.
Keyphrases
  • deep brain stimulation
  • white matter
  • parkinson disease
  • resting state
  • obsessive compulsive disorder
  • functional connectivity
  • endothelial cells
  • multiple sclerosis
  • induced pluripotent stem cells
  • case control