A Systematic Review of Clozapine Concentration-Dose Ratio from Therapeutic Drug Monitoring Studies in Children and Adolescents Treated with Clozapine for Mental Disorders.

Sara Jiménez-Fernández Manuel Gurpegui Christoph U Correll Jose De Leon Georgios Schoretsanitis

Published in: Therapeutic drug monitoring (2023)

Reports on clozapine therapeutic drug monitoring in children and adolescents are limited in number and quality. Future studies should focus on basic pharmacokinetic issues, such as stratification by sex, smoking, and relevant comedications with inductive or inhibitory properties.

Keyphrases

case control
current status
quality improvement
emergency department
newly diagnosed
drug induced