Architectural dysplasia in surgical margins and the risk of local relapse in oral cancer.
Irene H NautaLaura A N PeferoenRuud H BrakenhoffC René LeemansElisabeth BloemenaPublished in: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (2024)
Oral cavity squamous cell carcinoma arising in the background of architectural dysplasia displays relatively favorable clinical and histopathological characteristics. Nonetheless, the presence of architectural dysplasia in oral cavity squamous cell carcinoma surgical margins is associated with a higher risk of local relapse, indicating its clinical relevance.