Bio-conjugation of antioxidant peptide on surface-modified gold nanoparticles: a novel approach to enhance the radical scavenging property in cancer cell.

Sushma KalmodiaSuryanarayanan VandhanaB R Tejaswini RamaBalasubramanyam JayashreeT Sreenivasan SeethalakshmiVetrivel UmashankarWenrong YangColin J BarrowSubramanian KrishnakumarSailaja V Elchuri

Published in: Cancer nanotechnology (2016)

The effects of GNPs-Pep-A on ROS reduction and regulation of antioxidant genes confirmed that Vitis vinifera L. polyphenol-coated GNPs synergistically improve the radical scavenging properties and enhanced the apoptosis of cancer cell.

Keyphrases

oxidative stress
gold nanoparticles
anti inflammatory
cell death
dna damage
endoplasmic reticulum stress
genome wide
reactive oxygen species
reduced graphene oxide
gene expression
cell proliferation
dna methylation
genome wide identification