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Influence of Small Vessel Disease and Microstructural Integrity on Neurocognitive Functioning in Older Individuals: The DANTE Study Leiden.

J E F MoonenJessica C Foster-DingleyA A van den Berg-HuijsmansW de RuijterAnton J M de CraenJeroen van der GrondRoos C van der Mast
Published in: AJNR. American journal of neuroradiology (2016)
Microstructural integrity was associated with cognitive but not psychological dysfunction. Associations were independent of the conventional features of small vessel disease but attenuated after adjusting for brain volume.
Keyphrases
  • white matter
  • physical activity
  • multiple sclerosis
  • bipolar disorder
  • depressive symptoms
  • blood brain barrier
  • community dwelling