Absolute quantitative proteomics using the total protein approach to identify novel clinical immunohistochemical markers in renal neoplasms.
Susana JorgeJosé L CapeloWilliam LaFramboiseSwati SatturwarDimitrios KorentzelosSheldon BastackyGabriela Quiroga-GarzaRajiv DhirJacek R WiśniewskiCarlos LodeiroHugo Miguel SantosPublished in: BMC medicine (2021)
We demonstrate the utility of combining high-resolution MS and the TPA as potential new diagnostic tool in the pathology of renal neoplasms. A similar TPA approach may be implemented in any cancer study with solid biopsies.