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Design, Synthesis, Antifungal Activity and Molecular Docking of Novel Pyrazole-4-Carboxamides Containing Tertiary Alcohol and Difluoromethyl Moiety as Potential Succinate Dehydrogenase Inhibitors.

Yanhao SuTingting ZhangXinkun AnHaoyun MaMingan Wang
Published in: Pest management science (2023)
The excellent in vitro and in vivo inhibitory activities of novel pyrazole-4-carboxamide derivatives against SDH were reported for the first time, and they could be used as the potential lead compounds. This article is protected by copyright. All rights reserved.
Keyphrases
  • molecular docking
  • molecular dynamics simulations
  • human health
  • climate change
  • alcohol consumption