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Treatment of Candida infections with fluconazole in adult liver transplant recipients: Is TDM-guided dosing adaptation helpful?

Elda RighiAlessia CarneluttiUmberto BaccaraniAssunta SartorPiergiorgio CojuttiMatteo BassettiFederico Pea
Published in: Transplant infectious disease : an official journal of the Transplantation Society (2019)
Our study identified decreased fluconazole Cmin as a factor associated with negative outcomes in liver transplant recipients with Candida infection. TDM of fluconazole may be advisable in this patient population.
Keyphrases
  • candida albicans
  • biofilm formation
  • metabolic syndrome
  • combination therapy
  • pseudomonas aeruginosa
  • young adults
  • skeletal muscle
  • smoking cessation
  • insulin resistance
  • weight loss
  • replacement therapy