Spermidine enhances the efficacy of adjuvant in HBV vaccination in mice.
Daisuke ItoHiroyasu ItoTatsuya AndoYasuhiro SakaiTakayasu IdetaKen J IshiiTetsuya IshikawaMasahito ShimizuPublished in: Hepatology communications (2023)
These results indicate that the combination of HBV vaccine adjuvant and SPD induces a stronger humoral and cellular immune response through T-cell activation. These treatments may support the development of a strategy to completely eliminate HBV.