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Neurotoxicities associated with checkpoint inhibitors: Two case reports and a review of the literature.

Lisa M CordesNicole N DavarpanahLauren B ReomaBillel GasmiMartha QuezadoOmar I KhanAvindra NathAndrea B Apolo
Published in: Clinical case reports (2019)
We report a case of nivolumab-induced delayed-onset aseptic meningitis and a case of limbic encephalitis and peripheral nerve palsy with toxicity relapse 6 months after initial presentation. The atypical presentations contribute to our knowledge of these rare events and reinforce the necessity for vigilant monitoring and a multidisciplinary treatment approach.
Keyphrases
  • peripheral nerve
  • case report
  • healthcare
  • dna damage
  • oxidative stress
  • diabetic rats
  • cell cycle
  • drug induced
  • quality improvement
  • combination therapy
  • cerebrospinal fluid