Endothelial Dysfunction Is Related to Monocyte Activation in Antiretroviral-Treated People With HIV and HIV-Negative Adults in Kenya.

Tecla M TemuStephen J PolyakJerry S ZifodyaCelestine N WanjallaJohn R KoetheSarah MasyukoJerusha NyabiageJohn KinuthiaAna L GervassiJulius OyugiStephanie PageCarey Farquhar

Published in: Open forum infectious diseases (2020)

Despite viral suppression, African PWH have evidence of enhanced endothelial activation associated with sCD14, suggesting that monocyte activation plays a role in atherosclerotic plaque development. Future studies are needed to determine mechanistic pathways leading to monocyte activation in this population.

Keyphrases

hiv infected
hiv positive
human immunodeficiency virus
antiretroviral therapy
endothelial cells
hiv aids
dendritic cells
hepatitis c virus
hiv testing
sars cov
men who have sex with men
newly diagnosed