Outcomes of long-term von Willebrand factor prophylaxis use in von Willebrand disease: A systematic literature review.

Abdallah El AlayliRomina Brignardello PetersenNedaa M HusainatMohamad A KalotYazan AljabiriHani TurkmaniAlec BrittHussein El-KhechenShaneela ShahidJohn RollerShahrzad MotaghiRazan MansourAlberto TosettoRezan Abdul Kadir Michael A Laffan Angela C Weyand Frank W G LeebeekAlice ArapshianPeter KouidesPaula JamesNathan T ConnellVeronica H FloodReem A Mustafa

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2022)

VWD prophylaxis treatment seems to reduce the risk of spontaneous bleeding, epistaxis, and hospitalizations. More RCTs should be conducted to increase the certainty in these benefits.

Keyphrases

atrial fibrillation
type diabetes
adipose tissue
skeletal muscle
replacement therapy
metabolic syndrome
smoking cessation
glycemic control