Design, synthesis, and evaluation of a mitoxantrone probe (MXP) for biological studies.
Savanna WallinYongseok ChoiGloria E O BorgstahlAmarnath NatarajanPublished in: bioRxiv : the preprint server for biology (2023)
An 8-step synthesis was used to generate a biotinylated-mitoxantrone probe (MXP).A pulldown of MXP demonstrated selectivity for RAD52, but not Replication Protein A.Western blot confirmed the identity of the isolated protein, RAD52.