From SARS and MERS CoVs to SARS-CoV-2: Moving toward more biased codon usage in viral structural and nonstructural genes.

Mahmoud KandeelAbdelazim IbrahimMahmoud FayezMohammed Al-Nazawi

Published in: Journal of medical virology (2020)

Extreme bias and lower ENc values of SARS-CoV-2, especially in Spike, Envelope, and Mpro genes, are suggestive for higher gene expression efficiency, compared with SARS, bat SARS, and MERS CoVs.

Keyphrases

sars cov
respiratory syndrome coronavirus
gene expression
genome wide
dna methylation
genome wide identification
bioinformatics analysis
climate change
genome wide analysis
transcription factor