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Taxane Meets Propellane: First Chemical Synthesis of Highly Complex Diterpene Canataxpropellane.

Franziska ReußPhilipp Heretsch
Published in: Angewandte Chemie (International ed. in English) (2020)
The features of two iconic chemical classes are united in the structure of the highly complex diterpene canataxpropellane and set a daunting challenge that has been met by the Gaich group. Their daring strategy and its benefit to the field of terpene chemistry is presented and discussed in this Highlight.
Keyphrases
  • tyrosine kinase
  • metastatic breast cancer