Influence of sex, age and race on coronary and heart failure events in patients with diabetes and post-acute coronary syndrome.
Xavier RosselloJoão Pedro FerreiraFrancisca CaimariZohra LamiralAbhinav SharmaCyrus MehtaGeorge BakrisChristopher P CannonWilliam B WhiteFaiez ZannadPublished in: Clinical research in cardiology : official journal of the German Cardiac Society (2021)
Older adults, women and non-White patients with diabetes who are post-ACS are often underrepresented in RCTs. The risk for HF events was higher in older and non-White patients, with a trend towards significance in women, whereas only non-White patients (and not women and older patients) were at higher risk for MACE. Future trials should enrich enrollment of these persons at risk.
Keyphrases
- acute coronary syndrome
- polycystic ovary syndrome
- heart failure
- end stage renal disease
- pregnancy outcomes
- breast cancer risk
- physical activity
- ejection fraction
- newly diagnosed
- cervical cancer screening
- coronary artery
- coronary artery disease
- chronic kidney disease
- percutaneous coronary intervention
- pregnant women
- healthcare
- peritoneal dialysis
- antiplatelet therapy
- prognostic factors
- adipose tissue
- atrial fibrillation
- acute heart failure
- health insurance