Digital pathology assessment of kidney glomerular filtration barrier ultrastructure in an animal model of podocytopathy.
Aksel LaudonAnqi ZouZhaoze WangRicha SharmaXueping FanJiayi JiConnor KimYingzhe QianQin YeHui ChenJoel M HendersonChao ZhangVijaya B KolachalamaWeining LuPublished in: bioRxiv : the preprint server for biology (2024)
These results suggest that certain automated measurements enabled via deep learning-based digital pathology tools could distinguish healthy kidneys from those with podocytopathy. Our proposed method provides high-throughput, objective morphological analysis and could facilitate podocytopathy research and translate into clinical diagnosis.