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Digital pathology assessment of kidney glomerular filtration barrier ultrastructure in an animal model of podocytopathy.

Aksel LaudonAnqi ZouZhaoze WangRicha SharmaXueping FanJiayi JiConnor KimYingzhe QianQin YeHui ChenJoel M HendersonChao ZhangVijaya B KolachalamaWeining Lu
Published in: bioRxiv : the preprint server for biology (2024)
These results suggest that certain automated measurements enabled via deep learning-based digital pathology tools could distinguish healthy kidneys from those with podocytopathy. Our proposed method provides high-throughput, objective morphological analysis and could facilitate podocytopathy research and translate into clinical diagnosis.
Keyphrases
  • high throughput
  • deep learning
  • machine learning
  • artificial intelligence
  • single cell
  • diabetic nephropathy
  • high glucose
  • electron microscopy