Decreased Infliximab Concentrations in Patients With Inflammatory Bowel Disease Who Carry a Variable Number Tandem Repeat Polymorphism in the Neonatal Fc Receptor or Variant HLADQA1*05G>A Genotype.
Bethany ChoiMichael SeyTerry PonichMelanie BeatonRichard KimAze Suzanne WilsonPublished in: Inflammatory bowel diseases (2022)
FCGRT VNTR and HLADQA1*05G>A are associated with lower maintenance-phase infliximab concentrations, particularly among patients who carry both variants.