Multiomics analysis of the mdx/mTR mouse model of Duchenne muscular dystrophy.

Douglas W Van Pelt Yalda A KharazDylan C SarverLogan R EckhardtJustin T DzierzawskiNathaniel P DisserAlex N PiacentiniEithne J Comerford Brian McDonagh Christopher L Mendias

Published in: Connective tissue research (2020)

These findings highlight the utility of multiomics in studying muscle disease, and provide additional insight into the pathological changes in dystrophic muscles that might help to indirectly guide evidence-based nutritional or exercise prescription in DMD patients.

Keyphrases

duchenne muscular dystrophy
mouse model
end stage renal disease
muscular dystrophy
ejection fraction
newly diagnosed
peritoneal dialysis
skeletal muscle
high intensity
resistance training