The causal associations of circulating amino acids with blood pressure: a Mendelian randomization study.
Chenhao LinZhonghan SunZhendong MeiHailuan ZengManying ZhaoJianying HuMingfeng XiaTao HuangChaolong WangXin GaoYan ZhengPublished in: BMC medicine (2022)
This study provides evidence for causal impacts of genetically predicted circulating BCAAs and glycine levels on BP. Meanwhile, genetically predicted higher BP was associated with lower glycine levels. Further investigations are warranted to clarify the underlying mechanisms.