"Liquid Gold" - The unTAPped Potential of Cerebrospinal Fluid Analysis?
Isabella C Glitza OlivaHussein A TawbiPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Obtaining blood and cerebrospinal fluid is generally less invasive than standard tumor biopsy, and are increasingly used to develop surrogate biomarkers. Leptomeningeal disease, a devastating complication of cancer, represents a unique opportunity for using liquid biopsies for diagnosis, treatment, and to elucidate underlying mechanisms of resistance to therapy.See related article by Smalley et al., p. 2163.