Calycosin Induces Gastric Cancer Cell Apoptosis via the ROS-Mediated MAPK/STAT3/NF-κB Pathway.

Yu ZhangJian-Qiang ZhangTong ZhangHui XueWen-Bo ZuoYan-Nan LiYue ZhaoGeng SunZhong-Ren FuQing ZhangXue ZhaoYue TengAn-Qi WangJia-Zhu LiYing WangCheng-Hao Jin

Published in: OncoTargets and therapy (2021)

In summary, calycosin induces apoptosis via ROS-mediated MAPK/STAT3/NF-κB pathways, thereby exerting its anti-carcinogenic functions in GC cells.

Keyphrases

signaling pathway
pi k akt
induced apoptosis
cell proliferation
cell cycle arrest
oxidative stress
cell death
dna damage
lps induced
nuclear factor
mass spectrometry
endoplasmic reticulum stress
high resolution
simultaneous determination
tandem mass spectrometry
gas chromatography