Value of combined multiparametric MRI and FDG-PET/CT to identify well-responding rectal cancer patients before the start of neoadjuvant chemoradiation.
Niels W SchurinkLisa A MinMaaike BerbeeWouter van ElmptJoost J M van GriethuysenFrans C H BakersSander RobertiSimon R van KranenMax J LahayeMonique MaasGeerard L BeetsRegina G H Beets-TanDoenja M J LambregtsPublished in: European radiology (2020)
• A multivariable model incorporating the mrT-stage and quantitative features derived from baseline MRI can aid in identifying well-responding patients before the start of neoadjuvant chemoradiotherapy. • mrT-stage was the strongest predictor in the model and was complemented by the tumour volume and signal entropy calculated from T2W-MRI. • Adding quantitative features derived from pre-treatment PET/CT or DWI did not contribute to the model's predictive performance.
Keyphrases
- rectal cancer
- locally advanced
- end stage renal disease
- pet ct
- magnetic resonance imaging
- ejection fraction
- chronic kidney disease
- newly diagnosed
- contrast enhanced
- diffusion weighted imaging
- lymph node
- prognostic factors
- squamous cell carcinoma
- computed tomography
- high resolution
- combination therapy
- patient reported