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Risk factors and treatment outcomes of 239 patients with testicular granulosa cell tumors: a systematic review of published case series data.

Josias Bastian GroggKym SchneiderPeter-Karl BodeBenedikt KranzbühlerDaniel EberliTullio SulserJoerg BeyerAnja LorchThomas HermannsChristian Daniel Fankhauser
Published in: Journal of cancer research and clinical oncology (2020)
Juvenile tGrCT represent a benign entity whereas adult tGCTs have metastatic potential. Tumor size, presence of angiolymphatic invasion or gynecomastia represent risk factors for metastatic disease. The published literature supports the use of testis sparing surgery but there is only limited experience with adjuvant therapies. In the metastatic setting, the reviewed literature suggests that aggressive surgical and systemic treatment might cure patients.
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