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British Rhinological Society Consensus Guidance on the use of biological therapies for chronic rhinosinusitis with nasal polyps.

Claire HopkinsJo-Lyn McKenzieShahram AnariSean CarrieYujay RamakrishnanNaveed KaraCarl Martin PhilpottJonathan HobsonAli QureishiBenjamin StewRaj BhallaSimon B GaneAbigail WalkerPhil HarriesIain HathornValerie Lund
Published in: Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery (2021)
Although biologics are not currently available for the treatment of CRSwNP, the BRS Council have defined a group of patients who have higher rates of "failure" with current treatment pathways, higher resource use and are more likely to suffer with uncontrolled symptoms. We would urge NICE to consider approval of biologics for such indications without applying further restrictions on use.
Keyphrases
  • chronic rhinosinusitis
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease
  • peritoneal dialysis
  • physical activity
  • depressive symptoms