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Donor Treg expansion by liposomal α-galactosylceramide modulates Tfh cells and prevents sclerodermatous chronic graft-versus-host disease.

Hiroyuki SugiuraKen-Ichi MatsuokaTakuya FukumiYuichi SumiiTakumi KondoShuntaro IkegawaYusuke MeguriMiki IwamotoYasuhisa SandoMakoto NakamuraTomohiro TojiYasuyuki IshiiYoshinobu Maeda
Published in: Immunity, inflammation and disease (2021)
These data demonstrated an important coordination of T- and B-cell immunity in the pathogenesis of cGVHD and may provide a novel clinical strategy for the induction of immune tolerance after allogeneic HSCT.
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