Citicoline/Coenzyme Q10/Vitamin B3 Fixed Combination Exerts Synergistic Protective Effects on Neuronal Cells Exposed to Oxidative Stress.

Leonardo MastropasquaLuca Agnifili Claudio FerranteMatteo SacchiMichele Figus Gemma Caterina Maria Rossi Lorenza BresciaRaffaella AloiaGiustino Orlando

Published in: Nutrients (2022)

The present findings support the beneficial and synergistic effects of citicoline, CAVAQ10, and vitamin B3 in fixed combination in reducing inflammation and oxidation, and in stimulating neurotrophin production in neuronal cells.

Keyphrases

induced apoptosis
oxidative stress
cell cycle arrest
endoplasmic reticulum stress
signaling pathway
cancer therapy
cell death
hydrogen peroxide
nitric oxide
cell proliferation
pi k akt
diabetic rats
subarachnoid hemorrhage