Placental neurotrophin levels in gestational diabetes mellitus.

Anjali JadhavAmrita KhaireShridevi GunduNisha WadhwaniNomita ChandhiokSanjay GupteSadhana R Joshi

Published in: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience (2021)

This study for the first time demonstrates differential effects on neurotrophic factors such as BDNF and NGF in the placenta in pregnancies complicated by GDM. Alterations in the levels of placental neurotrophins in GDM deliveries may affect placental development and fetal brain growth. This has implications for increased risk for neurodevelopmental pathologies in later life.

Keyphrases

pregnant women
pregnancy outcomes
white matter
growth factor
resting state
multiple sclerosis
stress induced
cerebral ischemia