Transient Inhibition of the JAK/STAT Pathway Prevents B-ALL Development in Genetically Predisposed Mice.
Ana Casado-GarcíaMarta Isidro-HernándezNinad OakAndrea MayadoChristine Mann-RanJavier Raboso-GallegoSilvia Alemán-ArteagaAlexandra BuhlesDario SterkerElena G SánchezJorge Martínez-CanoOscar BlancoAlberto OrfaoDiego Alonso LópezJavier De Las RivasSusana RiescoPablo Prieto-MatosÁfrica González-MurilloFrancisco Javier García CriadoMaria-Begoña Garcia-CenadorThomas RadimerskiManuel Ramírez-OrellanaCésar CobaledaJun J YangCarolina Vicente-DueñasAndreas WeissKim E NicholsIsidro Sanchez-GarciaPublished in: Cancer research (2022)
JAK/STAT inhibition suppresses tumorigenesis in a B-ALL-susceptible mouse model, presenting a novel approach to prevent B-ALL onset.