Patient feedback and early outcome data with a novel tiered-binned model for multiplex breast cancer susceptibility testing.
Angela R BradburyLinda J Patrick-MillerBrian L EglestonLaura DiGiovanniJamie BrowerDiana HarrisEvelyn M StevensKara N MaxwellAbha KulkarniTyler ChavezAmanda BrandtKatherine L NathansonJacquelyn PowersJill E StopferKatherine L NathansonSusan M DomchekPublished in: Genetics in medicine : official journal of the American College of Medical Genetics (2015)
Some patients, particularly those without prior BRCA1/2 testing, decline multiplex testing. Most patients who proceeded with testing did not experience negative psychological responses, but larger studies are needed. The tiered-binned approach is an innovative genetic counseling and informed consent model for further study in the era of multiplex testing.Genet Med 18 1, 25-33.