Platelet-activating factor as an endogenous cofactor of food anaphylaxis.

Published in: BioFactors (Oxford, England) (2023)

Anaphylaxis is a severe, acute, life-threatening generalized or systemic hypersensitivity reaction. The incidence of anaphylaxis is increasing worldwide, with medications and food contributing to most cases. Physical exercise, acute infections, drugs, alcohol, and menstruation are the external cofactors associated with more severe systemic reaction. The aim of this review is to show that platelet-activating factor contributes to the development of severe anaphylactic reaction, and even to anaphylactic shock.

Keyphrases

drug induced
signaling pathway
early onset
liver failure
human health
risk factors
risk assessment
electron transfer
alcohol consumption