Tetrahydrobiopterin Restores Microvascular Dysfunction in Young Adult Binge Drinkers.

Chueh-Lung HwangJing-Tan BianLaurel A ThurTara A PetersMariann R PianoShane A Phillips

Published in: Alcoholism, clinical and experimental research (2019)

Microvascular dysfunction in young adult binge drinkers may be exacerbated with acute pathophysiological stimulus. These binge-induced dysfunctions may be reversed by tetrahydrobiopterin, which suggests a role of oxidative stress and/or uncoupled endothelial nitric oxide synthase in binge drinking.

Keyphrases

oxidative stress
young adults
nitric oxide synthase
diabetic rats
nitric oxide
alcohol consumption
drug induced
liver failure
dna damage
endothelial cells
childhood cancer
high glucose
respiratory failure
induced apoptosis
intensive care unit
aortic dissection