Elevated D-dimers and lack of anticoagulation predict PE in severe COVID-19 patients.

Basile MouhatMatthieu BesuttiKevin BouillerFranck GrilletCharles MonninFiona EcarnotJulien BehrGilles CapellierThibaud SoumagneSébastien Pili-FlouryGuillaume BeschGuillaume MoureyQuentin LepillerCatherine Chirouze Francois SchieleRomain ChopardNicolas Meneveau

Published in: The European respiratory journal (2020)

Elevated D-dimers (>2590 ng·mL-1) and absence of anticoagulant therapy predict PE in hospitalised COVID-19 patients with clinical signs of severity. These data strengthen the evidence base in favour of systematic anticoagulation, and suggest wider use of D-dimer guided CTPA to screen for PE in acutely ill hospitalised patients with COVID-19.

Keyphrases

atrial fibrillation
venous thromboembolism
sars cov
coronavirus disease
community acquired pneumonia
high throughput
electronic health record
early onset
big data
stem cells
mesenchymal stem cells
data analysis
drug induced
replacement therapy