Diffusion-weighted MRI and histogram analysis: assessment of response to neoadjuvant chemotherapy in nephroblastoma.
Andreas M HötkerYousef MazaheriAndré LollertJens-Peter SchenkJunting ZhengMarinela CapanuOguz AkinNorbert GrafGundula StaatzPublished in: Abdominal radiology (New York) (2021)
Pre-treatment skewness and kurtosis of ADC histogram analysis were significantly associated with a larger fraction of a blastemal remnant after neoadjuvant chemotherapy. These findings could be incorporated into a more personalized chemotherapeutic regime in these patients and offer prognostic information at the time of initial diagnosis.
Keyphrases
- neoadjuvant chemotherapy
- diffusion weighted
- contrast enhanced
- diffusion weighted imaging
- locally advanced
- lymph node
- sentinel lymph node
- magnetic resonance imaging
- end stage renal disease
- magnetic resonance
- ejection fraction
- computed tomography
- squamous cell carcinoma
- rectal cancer
- chronic kidney disease
- early stage
- peritoneal dialysis
- social media
- healthcare
- prognostic factors
- radiation therapy
- smoking cessation