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Liver-derived endocrine IGF-I is not critical for activation of skeletal muscle protein synthesis following oral feeding.
Britt-Marie Iresjö
Johan Svensson
Claes Ohlsson
Kent Lundholm
Published in:
BMC physiology (2013)
This study demonstrates that re-synthesis of muscle proteins following starvation is not critically dependent on endocrine liver-derived IGF-I.
Keyphrases
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skeletal muscle
insulin resistance
pi k akt
binding protein
growth hormone
type diabetes
cell proliferation
metabolic syndrome
adipose tissue
signaling pathway