Genomic Characterization and Clinical Outcomes of Patients with Peritoneal Metastases from the AACR GENIE Biopharma Collaborative Colorectal Cancer Registry.
Enrique Sanz-GarciaSamantha BrownJessica A LaveryJessica WeissHannah E FuchsAshley NewcombAsha PostleJeremy L WarnerMichele L LeNoue-NewtonShawn M SweeneyShirin PillaiCeleste YuChelsea NicholsBrooke MastrogiacomoRitika KundraNikolaus SchultzKenneth L KehlGregory J RielyDeborah SchragAnand GovindarajanKatherine S PanageasPhilippe L BedardPublished in: Cancer research communications (2024)
Utilizing the GENIE BPC registry, this study found that PM in patients with colorectal cancer occur more frequently in females and right-sided primary tumors and are associated with worse OS. In addition, we found a lower frequency of APC alterations and a higher frequency in MED12 alterations in patients with PM.