Pre-Clinical Studies of a Novel Bispecific Fusion Protein Targeting C3b and VEGF in Neovascular and Nonexudative AMD Models.
Yeri LeeDonggeon KimPhilip E D ChungMinkyeong LeeNahmju KimJihoon ChangByoung Chul LeePublished in: Ophthalmology and therapy (2024)
Unlike current therapies, KNP-301 is expected to cover patients with late-stage AMD of both neovascular and nonexudative AMD, and its long-term PK profile at the intravitreal chamber would allow convenience in the dosing interval of patients.