The prevalence and odds of bipolar disorder in women with polycystic ovary syndrome (PCO) disease: a systematic review and meta-analysis.

Zahra ShahrakiMohsen RastkarMohammad-Reza RamezanpourMahsa Ghajarzadeh

Published in: Archives of women's mental health (2024)

This systematic review and meta-analysis show that the pooled prevalence of bipolar disorder in women with PCO is 4%, and women with PCO are at a 2-fold higher risk of bipolar disorder.

Keyphrases

bipolar disorder
major depressive disorder
risk factors
polycystic ovary syndrome
clinical trial
type diabetes
adipose tissue
pregnant women
skeletal muscle
phase iii
open label
study protocol