Systemic doxycycline for pre-emptive treatment of anti-EGFR-related skin toxicity in patients with metastatic colorectal cancer receiving first-line panitumumab-based therapy: a post hoc analysis of the Valentino study.
Alessandra RaimondiSalvatore CoralloSara LonardiCarlotta AntoniottiLorenza RimassaAlessio AmatuMarco TampelliniPatrizia RaccaRoberto MurialdoMatteo ClavarezzaAlberto ZaniboniGiuseppe ToscanoGianluca TomaselloFausto PetrelliLorenzo AntonuzzoMonica GiordanoSaverio CinieriRaffaella LongariniMonica NigerMaria AntistaMargherita AmbrosiniFilippo PaganiMichele PrisciandaroGiovanni RandonFilippo de BraudMaria Di BartolomeoFilippo PietrantonioFederica MoranoPublished in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2021)
The adequate management of anti-EGFR-related skin toxicity is fundamental to optimize the outcome of mCRC patients, balancing the survival benefit with patients' quality of life, especially in the first-line setting.