A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism.

Jerod L PtacinLina MaCarolina E CaffaroNicole V AcuffKristine GermarPeter SeveryYanyan QuJose-Luis VelaXinming CaiKristine M San JoseHans R AerniDavid B ChenEan EscheTaylor K IsmailiRob HermanYelena PavlovaMichael J PenaJasmine NguyenLilia K KoriazovaLaura K ShawverIngrid B JosephJill MooneyMark PeakmanMarcos E Milla

Published in: Communications medicine (2024)

SAR'336 is a specific Treg activator, supporting its further development for the treatment of AI diseases.

Keyphrases

multiple sclerosis
artificial intelligence
nuclear factor
stem cells
immune response
replacement therapy
bone marrow
cell therapy