Size-changeable nanoprobes for the combined radiotherapy and photodynamic therapy of tumor.
Zhenyu HouMei ZhouYuanyuan MaXiaoxuan XuZhiqi ZhangShiwei LaiWenpei FanJinbing XieSheng-Hong JuPublished in: European journal of nuclear medicine and molecular imaging (2022)
The designed size-changeable nanoprobes BGBC showed excellent tumor accumulation and deep tumor penetration, resulting in a significant tumor suppression effect based on the combined RT and PDT. This study provides a novel strategy for dual delivery of radiotherapy sensitizers and photosensitizers into the deep tumor tissues and is promising for the accurate theranostics of tumor.