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Size-changeable nanoprobes for the combined radiotherapy and photodynamic therapy of tumor.

Zhenyu HouMei ZhouYuanyuan MaXiaoxuan XuZhiqi ZhangShiwei LaiWenpei FanJinbing XieSheng-Hong Ju
Published in: European journal of nuclear medicine and molecular imaging (2022)
The designed size-changeable nanoprobes BGBC showed excellent tumor accumulation and deep tumor penetration, resulting in a significant tumor suppression effect based on the combined RT and PDT. This study provides a novel strategy for dual delivery of radiotherapy sensitizers and photosensitizers into the deep tumor tissues and is promising for the accurate theranostics of tumor.
Keyphrases
  • photodynamic therapy
  • early stage
  • radiation therapy
  • fluorescence imaging
  • squamous cell carcinoma
  • high resolution
  • radiation induced
  • rectal cancer