Genetic characterization of suspected MODY patients in Tunisia by targeted next-generation sequencing.
Hamza DallaliSerena PezzilliMeriem HechmiOm Kalthoum SallemSahar ElouejHaifa JmelYosra Ben HalimaMariem CharguiMariem GharbiLuana MercuriFederica AlbericoTommaso MazzaAfaf BahlousMelika Ben AhmedHenda JamoussiAbdelmajid AbidVincenzo TrischittaSonia AbdelhakSabrina PrudenteRym KefiPublished in: Acta diabetologica (2019)
Our study is the first to investigate the clinical application of targeted next-generation sequencing for the diagnosis of MODY in Africa. The combination of this approach with a filtering/prioritization strategy made a step towards the identification of MODY mutations in the Tunisian population.