Sevoflurane preconditioning induces tolerance to brain ischemia partially via inhibiting thioredoxin-1 nitration.

Shiquan WangYuheng LiJinlong WeiPei LiQianzi Yang

Published in: BMC anesthesiology (2018)

Ischemic stroke reduces Trx-1 activity via post-translational nitrative modulation in rats. Sevoflurane preconditioning induces brain ischemic tolerance and anti-apoptosis by partially preserving Trx-1 activity via inhibiting nitration.

Keyphrases

cerebral ischemia
ischemia reperfusion injury
resting state
subarachnoid hemorrhage
signaling pathway
white matter
oxidative stress
blood brain barrier
brain injury
functional connectivity
endoplasmic reticulum stress
atrial fibrillation
cell cycle arrest
multiple sclerosis