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Peripartum management of patient with long QT3 after successful implantable cardioverter defibrillator device discharge resulting in device failure: a case report.

Melissa J LeeDanielle C MonteilMichael T Spooner
Published in: European heart journal. Case reports (2021)
There are many variants of the SCN5A gene mutations that can lead to different phenotypes and not all mutations are responsive to the same medications. In this case, Mexiletine and Propranolol, both of which have only recently shown to benefit certain variants or LQT3 respectively, were safely started during the 3rd trimester of pregnancy without harming the foetus.
Keyphrases
  • copy number
  • preterm birth
  • pregnancy outcomes
  • case report
  • gestational age
  • drug induced
  • gene expression
  • drug delivery