Single-Cell Characterization of the Immune Microenvironment of Melanoma Brain and Leptomeningeal Metastases.
Inna SmalleyZhihua ChenManali PhadkeJiannong LiXiaoqing YuClayton WyattBrittany EverndenJane L MessinaAmod SarnaikVernon K SondakChaomei ZhangVincent LawNam D TranArnold B EtameRobert J B MacaulayZeynep ErogluPeter A ForsythPaulo C RodriguezY Ann ChenKeiran S M SmalleyPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Our study provides the first atlas of two distinct sites of melanoma CNS metastases and defines the immune cell landscape that underlies the biology of this devastating disease.