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Pilot Study on Percutaneous Delivery of Recombinant Human Bone Morphongenetic Protein-2 Augments Fusion in a Nicotine-impaired Rabbit Fusion Model.

Sohrab VirkAvani VaishnavHiroshi KumagaiYu-Cheng YaoJames DowdellHarvinder SandhuFrank SchwabSheeraz Qureshi
Published in: Clinical spine surgery (2023)
Our study shows that injectable morselized absorbable collagen sponge/rhBMP-2 can create twice as much bone within a nicotine-impaired rabbit spine fusion model when delivered 4 weeks out from the time of surgery.
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