Non-Enzymatic Glucose Sensors Composed of Polyaniline Nanofibers with High Electrochemical Performance.
Nebras SobahiMd Mottahir AlamMohd ImranMohammad Ehtisham KhanAkbar MohammadTaeho YoonIbrahim M MehediMohammad A HussainMohammed J AbdulaalAhmad A JimanPublished in: Molecules (Basel, Switzerland) (2024)
The measurement of glucose concentration is a fundamental daily care for diabetes patients, and therefore, its detection with accuracy is of prime importance in the field of health care. In this study, the fabrication of an electrochemical sensor for glucose sensing was successfully designed. The electrode material was fabricated using polyaniline and systematically characterized using scanning electron microscopy, high-resolution transmission electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and UV-visible spectroscopy. The polyaniline nanofiber-modified electrode showed excellent detection ability for glucose with a linear range of 10 μM to 1 mM and a detection limit of 10.6 μM. The stability of the same electrode was tested for 7 days. The electrode shows high sensitivity for glucose detection in the presence of interferences. The polyaniline-modified electrode does not affect the presence of interferences and has a low detection limit. It is also cost-effective and does not require complex sample preparation steps. This makes it a potential tool for glucose detection in pharmacy and medical diagnostics.
Keyphrases
- electron microscopy
- high resolution
- label free
- carbon nanotubes
- healthcare
- loop mediated isothermal amplification
- blood glucose
- real time pcr
- type diabetes
- end stage renal disease
- reduced graphene oxide
- cardiovascular disease
- chronic kidney disease
- palliative care
- physical activity
- hydrogen peroxide
- quality improvement
- pain management
- adipose tissue
- solid state
- patient reported outcomes
- molecularly imprinted
- metabolic syndrome
- skeletal muscle
- chronic pain
- risk assessment
- health information
- social media
- low cost
- human health
- contrast enhanced