Improving the barrier function of damaged cultured urothelium using chondroitin sulfate.
Boy B RozenbergD A W JanssenC F J JansenJ A SchalkenJohn P F A HeesakkersPublished in: Neurourology and urodynamics (2019)
CS instillation improves the recovery of the urothelial barrier after damage in vitro. This functional experiment shows that CS improves recovery of damaged urothelial function, which supports the hypothesis behind the mechanism of action of GAG-replenishment therapy.